Management of sagittal synostosis in the Synostosis Research Group: baseline data and early outcomes

OBJECTIVE Sagittal synostosis is the most common form of isolated craniosynostosis. Although some centers have reported extensive experience with this condition, reports focused on a single center. In 2017, Synostosis Research Group (SynRG), multicenter collaborative network, was formed to study Here, authors report their early treating sagittal in network. The goals were describe practice patterns, identify variations, and generate hypotheses for future research. METHODS All patients clinical diagnosis who presented SynRG center between March 1, October 31, 2019, included. Follow-up information through 2020, Data extracted from prospectively maintained registry included baseline parameters, surgical adjuncts techniques, complications prior discharge, indications reoperation. analysis descriptive, using frequencies categorical variables means medians continuous variables. RESULTS Two hundred five had treatment at 5 different sites. One twenty-six treated strip craniectomy 79 total cranial vault remodeling. wide parietal wedge osteotomies (44%), remodeling procedure without forehead (63%). Preoperative mean cephalic indices (CIs) similar groups: 0.69 0.68 Thirteen percent other health problems. cohort, 81% received tranexamic acid required transfusion compared 94% did not receive acid. rates complication low all groups. Five (2%) an unintended change CI 0.09 0.06 remodeling; resulted greater group. CONCLUSIONS severity scaphocephaly across procedures Treatment methods varied, but both satisfactory postoperative CIs. Use may reduce need cases. technique seemed be associated CI. Both findings seem amenable testing randomized controlled trial.